|Homo sapiens Gene: C1QBP|
|Last Modified||2014-10-13 [Report errors or provide feedback]|
|Gene Name||complement component 1, q subcomponent binding protein|
|Synonyms||gC1Q-R; GC1QBP; gC1qR; HABP1; p32; SF2p32;|
complement component 1, q subcomponent binding protein
|Useful resources||Stemformatics EHFPI ImmGen|
Binds proteins involved in complement, coagulation, and kinin systems, as well as viral and bacterial pathogens including S. aureus protein A and when expressed on activated platelets may contribute directly to thrombosis, inflammation and endovascular infections
The human complement subcomponent C1q associates with C1r and C1s in order to yield the first component of the serum complement system. The protein encoded by this gene is known to bind to the globular heads of C1q molecules and inhibit C1 activation. This protein has also been identified as the p32 subunit of pre-mRNA splicing factor SF2, as well as a hyaluronic acid-binding protein. [provided by RefSeq, Jul 2008]
|Genomic Location||Chromosome 17:5432777-5448830|
|Number of Interactions||
This gene and/or its encoded proteins are associated with 164 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Formation of Fibrin Clot (Clotting Cascade) pathway
Intrinsic Pathway pathway
|UniProt Splice Variant|
|RNA Seq Atlas|