|Homo sapiens Gene: MYO1E|
|Last Modified||2014-10-13 [Report errors or provide feedback]|
|Gene Name||myosin IE|
|Synonyms||FSGS6; HuncM-IC; MYO1C;|
|Useful resources||Stemformatics EHFPI ImmGen|
This gene encodes a member of the nonmuscle class I myosins which are a subgroup of the unconventional myosin protein family. The unconventional myosin proteins function as actin-based molecular motors. Class I myosins are characterized by a head (motor) domain, a regulatory domain and a either a short or long tail domain. Among the class I myosins, this protein is distinguished by a long tail domain that is involved in crosslinking actin filaments. This protein localizes to the cytoplasm and may be involved in intracellular movement and membrane trafficking. Mutations in this gene are the cause of focal segmental glomerulosclerosis-6. This gene has been referred to as myosin IC in the literature but is distinct from the myosin IC gene located on chromosome 17. [provided by RefSeq, Jan 2012]
|Genomic Location||Chromosome 15:59132434-59372900|
|Number of Interactions||
This gene and/or its encoded proteins are associated with 33 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
|UniProt Splice Variant|
|RNA Seq Atlas||4643|