Homo sapiens Gene: DBNL
Summary
InnateDB Gene IDBG-14038.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DBNL
Gene Name drebrin-like
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000136279
Encoded Proteins
drebrin-like
drebrin-like
drebrin-like
drebrin-like
drebrin-like
drebrin-like
drebrin-like
drebrin-like
drebrin-like
drebrin-like
drebrin-like
drebrin-like
drebrin-like
drebrin-like
drebrin-like
drebrin-like
drebrin-like
drebrin-like
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 7:44044640-44069456
Strand Forward strand
Band p13
Transcripts
ENST00000441840 ENSP00000392113
ENST00000448521 ENSP00000411701
ENST00000456905 ENSP00000416421
ENST00000458579 ENSP00000403372
ENST00000440166 ENSP00000415173
ENST00000439983
ENST00000423561
ENST00000452943 ENSP00000405343
ENST00000439815 ENSP00000410681
ENST00000429716 ENSP00000400817
ENST00000441904 ENSP00000415395
ENST00000411855 ENSP00000390397
ENST00000432854 ENSP00000398931
ENST00000449997
ENST00000452661 ENSP00000397855
ENST00000464762 ENSP00000418006
ENST00000490734 ENSP00000417749
ENST00000498733 ENSP00000418978
ENST00000485932 ENSP00000418301
ENST00000468694 ENSP00000417653
ENST00000494774 ENSP00000419992
ENST00000497184
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 49 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 49 [view]
Protein-Protein 49 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
GO:0008047 enzyme activator activity
GO:0019904 protein domain specific binding
GO:0051015 actin filament binding
Biological Process
GO:0002376 immune system process
GO:0006897 endocytosis
GO:0006915 apoptotic process
GO:0006921 cellular component disassembly involved in execution phase of apoptosis
GO:0007257 activation of JUN kinase activity
GO:0007416 synapse assembly
GO:0016601 Rac protein signal transduction
GO:0048812 neuron projection morphogenesis
GO:0071800 podosome assembly
Cellular Component
GO:0000139 Golgi membrane
GO:0001726 ruffle
GO:0002102 podosome
GO:0005622 intracellular
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005938 cell cortex
GO:0014069 postsynaptic density
GO:0030027 lamellipodium
GO:0030054 cell junction
GO:0030425 dendrite
GO:0030665 clathrin-coated vesicle membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
TCR pathway
BCR pathway
TSLP pathway
REACTOME
Apoptotic execution phase pathway
Apoptosis pathway
Apoptotic cleavage of cellular proteins pathway
Caspase-mediated cleavage of cytoskeletal proteins pathway
KEGG
INOH
PID BIOCARTA
PID NCI
TCR signaling in na´ve CD4+ T cells
JNK signaling in the CD4+ TCR pathway
Cross-References
SwissProt
TrEMBL F2Z2V3 F8WBG8
UniProt Splice Variant
Entrez Gene 28988
UniGene Hs.436500 Hs.687566
RefSeq NM_001014436 NM_001284313 NM_001122956 NM_014063 NM_001284315
HUGO HGNC:2696
OMIM 610106
CCDS CCDS34623 CCDS64634 CCDS47579 CCDS34622 CCDS64633
HPRD 06588
IMGT
EMBL AC017116
GenPept
RNA Seq Atlas 102466985 28988