Version 5.4
Homo sapiens Gene: DBNL
Summary
InnateDB Gene IDBG-14038.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DBNL
Gene Name drebrin-like
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000136279
Encoded Proteins
IDBP-373410
drebrin-like
IDBP-373458
drebrin-like
IDBP-373459
drebrin-like
IDBP-373463
drebrin-like
IDBP-373465
drebrin-like
IDBP-373472
drebrin-like
IDBP-373474
drebrin-like
IDBP-373475
drebrin-like
IDBP-373477
drebrin-like
IDBP-373478
drebrin-like
IDBP-373485
drebrin-like
IDBP-373488
drebrin-like
IDBP-480589
drebrin-like
IDBP-484578
drebrin-like
IDBP-475053
drebrin-like
IDBP-478833
drebrin-like
IDBP-483381
drebrin-like
IDBP-474945
drebrin-like
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 7:44044640-44069456
Strand Forward strand
Band p13
Transcripts
ENST00000441840 ENSP00000392113
ENST00000448521 ENSP00000411701
ENST00000456905 ENSP00000416421
ENST00000458579 ENSP00000403372
ENST00000440166 ENSP00000415173
ENST00000439983
ENST00000423561
ENST00000452943 ENSP00000405343
ENST00000439815 ENSP00000410681
ENST00000429716 ENSP00000400817
ENST00000441904 ENSP00000415395
ENST00000411855 ENSP00000390397
ENST00000432854 ENSP00000398931
ENST00000449997
ENST00000452661 ENSP00000397855
ENST00000464762 ENSP00000418006
ENST00000490734 ENSP00000417749
ENST00000498733 ENSP00000418978
ENST00000485932 ENSP00000418301
ENST00000468694 ENSP00000417653
ENST00000494774 ENSP00000419992
ENST00000497184
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 49 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 49 [view]
Protein-Protein 49 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
GO:0008047 enzyme activator activity
GO:0019904 protein domain specific binding
GO:0051015 actin filament binding
Biological Process
GO:0002376 immune system process
GO:0006897 endocytosis
GO:0006915 apoptotic process
GO:0006921 cellular component disassembly involved in execution phase of apoptosis
GO:0007257 activation of JUN kinase activity
GO:0007416 synapse assembly
GO:0016601 Rac protein signal transduction
GO:0048812 neuron projection morphogenesis
GO:0071800 podosome assembly
Cellular Component
GO:0000139 Golgi membrane
GO:0001726 ruffle
GO:0002102 podosome
GO:0005622 intracellular
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005938 cell cortex
GO:0014069 postsynaptic density
GO:0030027 lamellipodium
GO:0030054 cell junction
GO:0030425 dendrite
GO:0030665 clathrin-coated vesicle membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000020476
View Gene Order
ENSBTAG00000017547
Not yet available
Pathways
NETPATH
NetPath_11
TCR pathway
NetPath_12
BCR pathway
NetPath_24
TSLP pathway
REACTOME
REACT_13541
Caspase-mediated cleavage of cytoskeletal proteins pathway
REACT_107
Apoptotic cleavage of cellular proteins pathway
REACT_995
Apoptotic execution phase pathway
REACT_578
Apoptosis pathway
KEGG
INOH
PID NCI
tcr_pathway
TCR signaling in naïve CD4+ T cells
tcrjnkpathway
JNK signaling in the CD4+ TCR pathway
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.436500 Hs.687566
RefSeq NM_001014436 NM_001122956 NM_001284313 NM_001284315 NM_014063
HUGO
OMIM
CCDS CCDS34622 CCDS34623 CCDS47579 CCDS64633 CCDS64634
HPRD 06588
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca