Homo sapiens Gene: DCP1B
Summary
InnateDB Gene IDBG-12054.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DCP1B
Gene Name DCP1 decapping enzyme homolog B (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000151065
Encoded Proteins
DCP1 decapping enzyme homolog B (S. cerevisiae)
DCP1 decapping enzyme homolog B (S. cerevisiae)
DCP1 decapping enzyme homolog B (S. cerevisiae)
decapping mRNA 1B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary DCP1B is a core component of the mRNA decapping complex, a key factor in the regulation of mRNA decay (Lykke-Andersen, 2002 [PubMed 12417715]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:1946054-2004535
Strand Reverse strand
Band p13.33
Transcripts
ENST00000280665 ENSP00000280665
ENST00000543381 ENSP00000445011
ENST00000540622 ENSP00000444374
ENST00000536665
ENST00000541700
ENST00000537725
ENST00000535873 ENSP00000482714
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 27 experimentally validated interaction(s) in this database.
Experimentally validated
Total 27 [view]
Protein-Protein 27 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0016787 hydrolase activity
Biological Process
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0010467 gene expression
GO:0016070 RNA metabolic process
GO:0016071 mRNA metabolic process
GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0016020 membrane
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathways
NETPATH
REACTOME
mRNA decay by 5' to 3' exoribonuclease pathway
Deadenylation-dependent mRNA decay pathway
Gene Expression pathway
KEGG
RNA degradation pathway
INOH
PID BIOCARTA
PID NCI
p73 transcription factor network
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.130934
RefSeq NM_152640 XM_006718971 XM_006718972
HUGO
OMIM
CCDS CCDS31727
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas