Version 5.4
Bos taurus Gene: WDR7
Summary
InnateDB Gene IDBG-644780.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol WDR7
Gene Name WD repeat-containing protein 7
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000004005
Encoded Proteins
IDBP-697470
WD repeat domain 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000091157:
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) that may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. The encoded protein forms the beta subunit of rabconnectin-3 and binds directly with Rab3A GDP/GTP exchange protein and indirectly with Rab3A GDP/GTP activating protein; these proteins are regulators of Rab3 small G protein family members involved in control of the calcium-dependant exocytosis of neurotransmitters. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 24:56467338-56817379
Strand Forward strand
Band
Transcripts
ENSBTAT00000005230 ENSBTAP00000005230
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
GO:0005515 protein binding
Biological Process
GO:0002244 hematopoietic progenitor cell differentiation
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000091157
View Gene Order
ENSMUSG00000040560
View Gene Order
Cross-References
SwissProt
TrEMBL E1BEC1
UniProt Splice Variant
Entrez Gene 536469
UniGene Bt.32876
RefSeq NM_001206098 XM_005224233 XM_005224234 XM_005224235
HUGO HGNC:13490
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02057122 DAAA02057123 DAAA02057124 DAAA02057125
GenPept
RNA Seq Atlas 536469

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca