Version 5.4
Bos taurus Gene: FAN1
Summary
InnateDB Gene IDBG-630438.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FAN1
Gene Name fanconi-associated nuclease 1
Synonyms MTMR15
Species Bos taurus
Ensembl Gene ENSBTAG00000009855
Encoded Proteins
IDBP-681891
myotubularin related protein 15
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000198690:
This gene encodes a member of the myotubularin-related class 1 cysteine-based protein tyrosine phosphatases. The encoded protein may be catalytically inactive. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 21:27922210-27945107
Strand Forward strand
Band
Transcripts
ENSBTAT00000035195 ENSBTAP00000035073
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0008409 5'-3' exonuclease activity
GO:0016788 hydrolase activity, acting on ester bonds
GO:0017108 5'-flap endonuclease activity
GO:0043130 ubiquitin binding
Biological Process
GO:0000724 double-strand break repair via homologous recombination
GO:0000737 DNA catabolic process, endonucleolytic
GO:0006281 DNA repair
GO:0006289 nucleotide-excision repair
GO:0033683 nucleotide-excision repair, DNA incision
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000198690
View Gene Order
ENSMUSG00000033458
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
fanconi_pathway
Fanconi anemia pathway
Cross-References
SwissProt
TrEMBL F1MZ88
UniProt Splice Variant
Entrez Gene 508171
UniGene Bt.4066
RefSeq NM_001164670 XM_005221870 XM_005221872
HUGO HGNC:29170
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02052353
GenPept
RNA Seq Atlas 508171

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca