Mus musculus Gene: Snap23 | |||||||||||||||||||||||
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Summary | |||||||||||||||||||||||
InnateDB Gene | IDBG-201120.6 | ||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
Gene Symbol | Snap23 | ||||||||||||||||||||||
Gene Name | synaptosomal-associated protein 23 | ||||||||||||||||||||||
Synonyms | 23kDa; AA408749; SNAP-23; Sndt; Syndet | ||||||||||||||||||||||
Species | Mus musculus | ||||||||||||||||||||||
Ensembl Gene | ENSMUSG00000027287 | ||||||||||||||||||||||
Encoded Proteins |
synaptosomal-associated protein 23
synaptosomal-associated protein 23
synaptosomal-associated protein 23
synaptosomal-associated protein 23
synaptosomal-associated protein 23
synaptosomal-associated protein 23
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Protein Structure |
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Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
InnateDB Annotation from Orthologs | |||||||||||||||||||||||
Summary |
[Homo sapiens] SNAP23 phosphorylation by IKBKB regulates mast cell degranulation and anaphylactic reactions.
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Entrez Gene | |||||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000092531:
Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of 25 kDa), form a complex which serves as a binding site for the general membrane fusion machinery. Synaptobrevin/VAMP and syntaxin are believed to be involved in vesicular transport in most, if not all cells, while SNAP25 is present almost exclusively in the brain, suggesting that a ubiquitously expressed homolog of SNAP25 exists to facilitate transport vesicle/target membrane fusion in other tissues. The protein encoded by this gene is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||
Genomic Location | Chromosome 2:120567671-120601255 | ||||||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||||||
Band | E5 | ||||||||||||||||||||||
Transcripts | |||||||||||||||||||||||
Interactions | |||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
They are also associated with 45 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||
REACTOME |
Membrane Trafficking pathway
trans-Golgi Network Vesicle Budding pathway
Clathrin derived vesicle budding pathway
Translocation of GLUT4 to the plasma membrane pathway
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KEGG |
SNARE interactions in vesicular transport pathway
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INOH | |||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||
REACTOME |
Translocation of GLUT4 to the plasma membrane pathway
Clathrin derived vesicle budding pathway
trans-Golgi Network Vesicle Budding pathway
Membrane Trafficking pathway
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KEGG |
SNARE interactions in vesicular transport pathway
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INOH | |||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||
Cross-References | |||||||||||||||||||||||
SwissProt | O09044 | ||||||||||||||||||||||
TrEMBL | A2AKH4 B0R029 B0R030 | ||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||
Entrez Gene | 20619 | ||||||||||||||||||||||
UniGene | Mm.398640 Mm.413475 | ||||||||||||||||||||||
RefSeq | NM_001177793 NM_001177792 NM_009222 XM_006499054 XM_006499055 XM_006499056 | ||||||||||||||||||||||
OMIM | |||||||||||||||||||||||
CCDS | CCDS16622 CCDS50681 | ||||||||||||||||||||||
HPRD | |||||||||||||||||||||||
IMGT | |||||||||||||||||||||||
MGI ID | MGI:109356 | ||||||||||||||||||||||
MGI Symbol | Snap23 | ||||||||||||||||||||||
EMBL | AB000822 AB007444 AF007169 AF213251 AF213252 AF213253 AF213254 AF213255 AF213256 AF213257 AK019162 AL772299 BC070456 CH466519 U73143 | ||||||||||||||||||||||
GenPept | AAB53597 AAB62932 AAF23503 AAH70456 BAA20345 BAB31577 BAF91555 EDL28001 | ||||||||||||||||||||||
RNA Seq Atlas | 20619 | ||||||||||||||||||||||