Version 5.4
Mus musculus Gene: Pitpna
Summary
InnateDB Gene IDBG-200235.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pitpna
Gene Name phosphatidylinositol transfer protein, alpha
Synonyms Pitpn; vb; vibrator
Species Mus musculus
Ensembl Gene ENSMUSG00000017781
Encoded Proteins
IDBP-200237
phosphatidylinositol transfer protein, alpha
IDBP-539196
phosphatidylinositol transfer protein, alpha
IDBP-719168
IDBP-717423
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000174238:
This gene encodes a member of a family of lipid-binding proteins that transfer molecules of phosphatidylinositol or phosphatidylcholine between membrane surfaces. The protein is implicated in phospholipase C signaling and in the production of phosphatidylinositol 3,4,5-trisphosphate (PIP3) by phosphoinositide-3-kinase.[provided by RefSeq, Sep 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:75588097-75628804
Strand Forward strand
Band B5
Transcripts
ENSMUST00000102509 ENSMUSP00000099567
ENSMUST00000143219 ENSMUSP00000115723
ENSMUST00000140841
ENSMUST00000153768
ENSMUST00000179445 ENSMUSP00000137601
ENSMUST00000179521 ENSMUSP00000137510
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005543 phospholipid binding
GO:0008289 lipid binding
Biological Process
GO:0006810 transport
Cellular Component
GO:0005622 intracellular
GO:0005829 cytosol
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000174238
View Gene Order
ENSBTAG00000011480
Not yet available
Pathways
NETPATH
REACTOME
REACT_229826
Netrin-1 signaling pathway
REACT_230631
Role of second messengers in netrin-1 signaling pathway
REACT_261444
Axon guidance pathway
REACT_188576
Developmental Biology pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_4
EGFR1 pathway
REACTOME
REACT_22228
Role of second messengers in netrin-1 signaling pathway
REACT_22237
Netrin-1 signaling pathway
REACT_111045
Developmental Biology pathway
REACT_18266
Axon guidance pathway
KEGG
INOH
PID NCI
netrin_pathway
Netrin-mediated signaling events
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.3128 Mm.397024 Mm.405389 Mm.475212
RefSeq NM_008850
OMIM
CCDS CCDS25052
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca