Version 5.4
Mus musculus Gene: Pkdrej
Summary
InnateDB Gene IDBG-170723.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pkdrej
Gene Name polycystic kidney disease (polycystin) and REJ (sperm receptor for egg jelly homolog, sea urchin)
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000052496
Encoded Proteins
IDBP-170725
polycystic kidney disease (polycystin) and REJ (sperm receptor for egg jelly homolog, sea urchin)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000130943:
This intronless gene encodes a member of the polycystin protein family. The encoded protein contains 11 transmembrane domains, a receptor for egg jelly (REJ) domain, a G-protein-coupled receptor proteolytic site (GPS) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. This protein may play a role in human reproduction. Alternative splice variants have been described but their biological natures have not been determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:85814676-85821733
Strand Reverse strand
Band E2
Transcripts
ENSMUST00000064370 ENSMUSP00000086352
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005216 ion channel activity
GO:0005262 calcium channel activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
GO:0006811 ion transport
GO:0050982 detection of mechanical stimulus
GO:0055085 transmembrane transport
GO:0060046 regulation of acrosome reaction
GO:0070588 calcium ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000130943
View Gene Order
ENSBTAG00000008066
Not yet available
Cross-References
SwissProt
TrEMBL F8VQF3
UniProt Splice Variant
Entrez Gene 18766
UniGene Mm.89965
RefSeq NM_011105
OMIM
CCDS CCDS27723
HPRD
IMGT
MGI ID MGI:1338786
MGI Symbol Pkdrej
EMBL AC117784
GenPept
RNA Seq Atlas 18766

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca