Version 5.4
Mus musculus Gene: Specc1l
Summary
InnateDB Gene IDBG-162501.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Specc1l
Gene Name sperm antigen with calponin homology and coiled-coil domains 1-like
Synonyms 4930470P14Rik; 4932439K10Rik; 9530057A13Rik; AI317249; Cytsa; mKIAA0376
Species Mus musculus
Ensembl Gene ENSMUSG00000033444
Encoded Proteins
IDBP-162503
sperm antigen with calponin homology and coiled-coil domains 1-like
IDBP-270914
sperm antigen with calponin homology and coiled-coil domains 1-like
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000100014:
This gene encodes a coiled-coil domain containing protein. The encoded protein may play a critical role in actin-cytoskeletal reorganization during facial morphogenesis. Mutations in this gene are a cause of oblique facial clefting-1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
This gene encodes a coiled-coil domain containing protein. The encoded protein may play a critical role in actin-cytoskeletal reorganization during facial morphogenesis. Mutations in this gene are a cause of oblique facial clefting-1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A read-through transcript composed of SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1-like) and the downstream ADORA2A (adenosine A2a receptor) gene sequence has been identified, but it is thought to be non-coding. [provided by RefSeq, Jun 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:75212073-75312399
Strand Forward strand
Band C1
Transcripts
ENSMUST00000040105 ENSMUSP00000045099
ENSMUST00000105421 ENSMUSP00000101061
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
GO:0046983 protein dimerization activity
Biological Process
GO:0007026 negative regulation of microtubule depolymerization
GO:0007049 cell cycle
GO:0007155 cell adhesion
GO:0016477 cell migration
GO:0030036 actin cytoskeleton organization
GO:0030835 negative regulation of actin filament depolymerization
GO:0051301 cell division
GO:0060325 face morphogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0005815 microtubule organizing center
GO:0005819 spindle
GO:0005921 gap junction
GO:0015629 actin cytoskeleton
GO:0015630 microtubule cytoskeleton
GO:0031941 filamentous actin
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000100014
View Gene Order
ENSBTAG00000021656
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.27716
RefSeq NM_001145826 NM_153406 XM_006514252
OMIM
CCDS CCDS48598 CCDS48599
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca