Version 5.4
Mus musculus Gene: Creb5
Summary
InnateDB Gene IDBG-148452.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Creb5
Gene Name cAMP responsive element binding protein 5
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000053007
Encoded Proteins
IDBP-148458
cAMP responsive element binding protein 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000146592:
The product of this gene belongs to the CRE (cAMP response element)-binding protein family. Members of this family contain zinc-finger and bZIP DNA-binding domains. The encoded protein specifically binds to CRE as a homodimer or a heterodimer with c-Jun or CRE-BP1, and functions as a CRE-dependent trans-activator. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:53573384-53696007
Strand Forward strand
Band B3
Transcripts
ENSMUST00000047450 ENSMUSP00000038532
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0045444 fat cell differentiation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0060612 adipose tissue development
Cellular Component
GO:0005634 nucleus
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000146592
View Gene Order
ENSBTAG00000018909
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu05215
Prostate cancer pathway
mmu05016
Huntington's disease pathway
mmu04962
Vasopressin-regulated water reabsorption pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa05215
Prostate cancer pathway
hsa05016
Huntington's disease pathway
hsa04962
Vasopressin-regulated water reabsorption pathway
INOH
PID NCI
Cross-References
SwissProt Q8K1L0
TrEMBL
UniProt Splice Variant
Entrez Gene 231991
UniGene
RefSeq NM_172728
OMIM
CCDS CCDS20153
HPRD
IMGT
MGI ID MGI:2443973
MGI Symbol Creb5
EMBL AK052451 AK154148 AK155537 AK170766 BC029022
GenPept AAH29022 BAC34998 BAE32408 BAE33314 BAE42016
RNA Seq Atlas 231991

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca