InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Bmi1

Summary

InnateDB Gene

IDBG-139744.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Bmi1

Gene Name

Bmi1 polycomb ring finger oncogene

Synonyms

AW546694; Bmi-1; Pcgf4

Species

Mus musculus

Ensembl Gene

ENSMUSG00000026739

Encoded Proteins

IDBP-139746

Bmi1 polycomb ring finger oncogene

IDBP-251314

Bmi1 polycomb ring finger oncogene

IDBP-536042

Bmi1 polycomb ring finger oncogene

IDBP-542607

Bmi1 polycomb ring finger oncogene

IDBP-537825

Bmi1 polycomb ring finger oncogene

IDBP-536729

Bmi1 polycomb ring finger oncogene

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000168283:
This locus represents naturally occurring read-through transcription between the neighboring COMM domain-containing protein 3 and polycomb complex protein BMI-1 genes on chromosome 10. The read-through transcript produces a fusion protein that shares sequence identity with each individual gene product. [provided by RefSeq, Feb 2011]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 2:18677018-18686629

Strand

Forward strand

Band

Transcripts

ENSMUST00000028071	ENSMUSP00000028071
ENSMUST00000051929	ENSMUSP00000110300
ENSMUST00000132014
ENSMUST00000150834	ENSMUSP00000119331
ENSMUST00000156284	ENSMUSP00000118730
ENSMUST00000134734	ENSMUSP00000121876
ENSMUST00000147365	ENSMUSP00000118273

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 51 experimentally validated interaction(s) in this database.
They are also associated with 65 interaction(s) predicted by orthology.

Experimentally validated
Total	51 [view]
Protein-Protein	49 [view]
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	1 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	65 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003682	chromatin binding
GO:0004842	ubiquitin-protein transferase activity
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0043565	sequence-specific DNA binding
GO:0046872	metal ion binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0001501	skeletal system development
GO:0001701	in utero embryonic development
GO:0006306	DNA methylation
GO:0006351	transcription, DNA-templated
GO:0006959	humoral immune response
GO:0007420	brain development
GO:0009987	cellular process
GO:0016573	histone acetylation
GO:0016574	histone ubiquitination
GO:0021903	rostrocaudal neural tube patterning
GO:0030890	positive regulation of B cell proliferation
GO:0033092	positive regulation of immature T cell proliferation in thymus
GO:0048103	somatic stem cell division
GO:0048704	embryonic skeletal system morphogenesis
GO:0048706	embryonic skeletal system development
GO:0051443	positive regulation of ubiquitin-protein transferase activity
GO:2001234	negative regulation of apoptotic signaling pathway