Version 5.4
Mus musculus Gene: Cdh6
Summary
InnateDB Gene IDBG-130513.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cdh6
Gene Name cadherin 6
Synonyms cad6; cadherin-6; K-cadherin
Species Mus musculus
Ensembl Gene ENSMUSG00000039385
Encoded Proteins
IDBP-130515
cadherin 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000113361:
This gene encodes a member of the cadherin superfamily. Cadherins are membrane glycoproteins that mediate homophilic cell-cell adhesion and play critical roles in cell differentiation and morphogenesis. The encoded protein is a type II cadherin and may play a role in kidney development as well as endometrium and placenta formation. Decreased expression of this gene may be associated with tumor growth and metastasis. [provided by RefSeq, May 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:13034200-13173639
Strand Reverse strand
Band A1
Transcripts
ENSMUST00000036439 ENSMUSP00000037113
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
Biological Process
GO:0007156 homophilic cell adhesion
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000113361
View Gene Order
ENSBTAG00000012992
Not yet available
Pathways
NETPATH
REACTOME
REACT_248094
Cell-cell junction organization pathway
REACT_230395
Adherens junctions interactions pathway
REACT_241978
Cell junction organization pathway
REACT_223082
Cell-Cell communication pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_19195
Adherens junctions interactions pathway
REACT_111155
Cell-Cell communication pathway
REACT_20676
Cell junction organization pathway
REACT_19331
Cell-cell junction organization pathway
REACT_214866
Cell junction organization pathway
REACT_206475
Cell-Cell communication pathway
REACT_207240
Cell-cell junction organization pathway
REACT_212282
Adherens junctions interactions pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt P97326
TrEMBL Q3UYK5
UniProt Splice Variant
Entrez Gene 12563
UniGene Mm.57048
RefSeq NM_007666 XM_006520017
OMIM
CCDS CCDS27393
HPRD
IMGT
MGI ID MGI:107435
MGI Symbol Cdh6
EMBL AK134611 BC107013 D82029 U67399
GenPept AAB07550 AAI07014 BAA11516 BAE22207
RNA Seq Atlas 12563

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca