Version 5.4
Homo sapiens Gene: SEPT3
Summary
InnateDB Gene IDBG-9541.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SEPT3
Gene Name septin 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000100167
Encoded Proteins
IDBP-237530
septin 3
IDBP-237532
septin 3
IDBP-237534
septin 3
IDBP-293174
septin 3
IDBP-378492
septin 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene belongs to the septin family of GTPases. Members of this family are required for cytokinesis. Expression is upregulated by retinoic acid in a human teratocarcinoma cell line. The specific function of this gene has not been determined. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 22:41976272-41998221
Strand Forward strand
Band q13.2
Transcripts
ENST00000396426 ENSP00000379704
ENST00000396425 ENSP00000379703
ENST00000396417 ENSP00000379695
ENST00000406029 ENSP00000383956
ENST00000449288 ENSP00000391416
ENST00000460267
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0007049 cell cycle
GO:0051301 cell division
Cellular Component
GO:0030054 cell junction
GO:0031105 septin complex
GO:0045202 synapse
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000022456
View Gene Order
ENSBTAG00000013173
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa05100
Bacterial invasion of epithelial cells pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.120483
RefSeq NM_019106 NM_145733
HUGO
OMIM
CCDS CCDS14026 CCDS14027
HPRD 10515
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca