Homo sapiens Protein: SEPT3
Summary
InnateDB Protein IDBP-237532.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SEPT3
Protein Name septin 3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000379703
InnateDB Gene IDBG-9541 (SEPT3)
Protein Structure
UniProt Annotation
Function Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). {ECO:0000250, ECO:0000305}.
Subcellular Localization Cytoplasm. Cytoplasm, cytoskeleton {ECO:0000250}. Cell junction, synapse {ECO:0000250}.
Disease Associations
Tissue Specificity Brain-specific. {ECO:0000269PubMed:11322766, ECO:0000269PubMed:15915442}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0007049 cell cycle
GO:0051301 cell division
Cellular Component
GO:0030054 cell junction
GO:0031105 septin complex
GO:0045202 synapse
Protein Structure and Domains
PDB ID
InterPro IPR000038 Cell division protein GTP binding
IPR004881 Ribosome biogenesis GTPase RsgA, putative
IPR006703 AIG1
IPR008114 Septin 3
IPR016491 Septin
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00735
PF03193
PF04548
PRINTS PR01741
PIRSF PIRSF006698
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9UH03
PhosphoSite PhosphoSite-Q9UH03
TrEMBL B1AHR2
UniProt Splice Variant
Entrez Gene 55964
UniGene Hs.120483
RefSeq NP_061979
HUGO HGNC:10750
OMIM 608314
CCDS CCDS14027
HPRD 10515
IMGT
EMBL AB209152 AF285107 AF285108 AF285109 AK290037 AL833942 BC111779 CH471095 CR456572 Z99716
GenPept AAG00517 AAG00518 AAG00519 AAI11780 BAD92389 BAF82726 CAD38797 CAG30458 CAI41693 CAQ07552 EAW60479 EAW60480