Version 5.4
Homo sapiens Protein: SEPT3
Summary
InnateDB Protein IDBP-237534.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SEPT3
Protein Name septin 3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000379695
InnateDB Gene IDBG-9541 (SEPT3)
Protein Structure
UniProt Annotation
Function Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). {ECO:0000250, ECO:0000305}.
Subcellular Localization Cytoplasm. Cytoplasm, cytoskeleton {ECO:0000250}. Cell junction, synapse {ECO:0000250}.
Disease Associations
Tissue Specificity Brain-specific. {ECO:0000269PubMed:11322766, ECO:0000269PubMed:15915442}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005525 GTP binding
Biological Process
GO:0007049 cell cycle
GO:0051301 cell division
Cellular Component
GO:0030054 cell junction
GO:0031105 septin complex
GO:0045202 synapse
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9UH03
PhosphoSite PhosphoSite-Q9UH03
TrEMBL
UniProt Splice Variant
Entrez Gene 55964
UniGene Hs.120483
RefSeq
HUGO HGNC:10750
OMIM 608314
CCDS
HPRD 10515
IMGT
EMBL AB209152 AF285107 AF285108 AF285109 AL833942 BC111779 CH471095 CR456572 Z99716
GenPept AAG00517 AAG00518 AAG00519 AAI11780 BAD92389 CAD38797 CAG30458 CAI41693 CAQ07552 EAW60480

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca