InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: GNA12

Summary

InnateDB Gene

IDBG-7130.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GNA12

Gene Name

guanine nucleotide binding protein (G protein) alpha 12

Synonyms

gep; NNX3; RMP

Species

Homo sapiens

Ensembl Gene

ENSG00000146535

Encoded Proteins

IDBP-7132

guanine nucleotide binding protein (G protein) alpha 12

IDBP-292553

guanine nucleotide binding protein (G protein) alpha 12

IDBP-292555

guanine nucleotide binding protein (G protein) alpha 12

IDBP-361890

guanine nucleotide binding protein (G protein) alpha 12

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.

Gene Information

Type

Protein coding

Genomic Location

Chromosome 7:2728112-2844324

Strand

Reverse strand

Band

p22.2

Transcripts

ENST00000275364	ENSP00000275364
ENST00000407904	ENSP00000385935
ENST00000407653	ENSP00000386054
ENST00000447791	ENSP00000391462
ENST00000491117
ENST00000496740
ENST00000471281
ENST00000485329

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 40 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	40 [view]
Protein-Protein	35 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	2 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003924	GTPase activity
GO:0004871	signal transducer activity
GO:0005515	protein binding
GO:0005525	GTP binding
GO:0019001	guanyl nucleotide binding
GO:0031683	G-protein beta/gamma-subunit complex binding
GO:0031752	D5 dopamine receptor binding
GO:0046872	metal ion binding

Biological Process

GO:0001701	in utero embryonic development
GO:0006184	GTP catabolic process
GO:0007165	signal transduction
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007266	Rho protein signal transduction
GO:0007596	blood coagulation
GO:0008360	regulation of cell shape
GO:0010762	regulation of fibroblast migration
GO:0030154	cell differentiation
GO:0030168	platelet activation
GO:0032006	regulation of TOR signaling
GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0035556	intracellular signal transduction
GO:0042493	response to drug
GO:0042733	embryonic digit morphogenesis