Version 5.4
Homo sapiens Protein: GNA12
Summary
InnateDB Protein IDBP-361890.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GNA12
Protein Name guanine nucleotide binding protein (G protein) alpha 12
Synonyms gep; NNX3; RMP;
Species Homo sapiens
Ensembl Protein ENSP00000391462
InnateDB Gene IDBG-7130 (GNA12)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 40 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 40 [view]
Protein-Protein 35 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 2 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0004871 signal transducer activity
GO:0019001 guanyl nucleotide binding
GO:0031683 G-protein beta/gamma-subunit complex binding
Biological Process
GO:0006184 GTP catabolic process
GO:0007165 signal transduction
GO:0007186 G-protein coupled receptor signaling pathway
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR011025 G protein alpha subunit, helical insertion
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL C9J2Y7
UniProt Splice Variant
Entrez Gene 2768
UniGene Hs.608358
RefSeq
HUGO HGNC:4380
OMIM 604394
CCDS
HPRD 05093
IMGT
EMBL AC006028
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca