Version 5.4
Bos taurus Protein: SPRED1
Summary
InnateDB Protein IDBP-698964.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SPRED1
Protein Name sprouty-related, EVH1 domain containing 1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000043442
InnateDB Gene IDBG-646185 (SPRED1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005173 stem cell factor receptor binding
GO:0005515 protein binding
GO:0019901 protein kinase binding
GO:0019902 phosphatase binding
GO:0030291 protein serine/threonine kinase inhibitor activity
Biological Process
GO:0000188 inactivation of MAPK activity
GO:0007275 multicellular organismal development
GO:0009966 regulation of signal transduction
GO:0010801 negative regulation of peptidyl-threonine phosphorylation
GO:0010923 negative regulation of phosphatase activity
GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator
GO:0090311 regulation of protein deacetylation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR000697 WH1/EVH1
IPR007875 Sprouty
PFAM PF00568
PF05210
PRINTS
PIRSF
SMART SM00461
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1MH60
UniProt Splice Variant
Entrez Gene 519882
UniGene Bt.72217
RefSeq NP_001179445
HUGO HGNC:20249
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02028504
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca