Version 5.4
Bos taurus Protein: UBE3A
Summary
InnateDB Protein IDBP-679901.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UBE3A
Protein Name ubiquitin-protein ligase E3A
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000046597
InnateDB Gene IDBG-628537 (UBE3A)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 92 interaction(s) predicted by orthology.
Predicted by orthology
Total 92 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003713 transcription coactivator activity
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0016874 ligase activity
Biological Process
GO:0001541 ovarian follicle development
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0016567 protein ubiquitination
GO:0030521 androgen receptor signaling pathway
GO:0035037 sperm entry
GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0051865 protein autoubiquitination
GO:0060736 prostate gland growth
GO:0070936 protein K48-linked ubiquitination
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR000569 HECT
IPR017134 Ubiquitin-protein ligase E6-AP
PFAM PF00632
PRINTS
PIRSF PIRSF037201
SMART SM00119
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q52UL2
UniProt Splice Variant
Entrez Gene 533136
UniGene Bt.91993
RefSeq NP_001091932
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AY948554 BC134678 DAAA02051638
GenPept AAI34679 AAX86799

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca