InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Bid

Summary

InnateDB Protein

IDBP-540652.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Bid

Protein Name

BH3 interacting domain death agonist

Synonyms

2700049M22Rik; AI875481; AU022477;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000117529

InnateDB Gene

IDBG-184076 (Bid)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
They are also associated with 47 interaction(s) predicted by orthology.

Experimentally validated
Total	22 [view]
Protein-Protein	21 [view]
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	47 [view]

Gene Ontology

Molecular Function

Accession

GO Term

Biological Process

GO:0001836	release of cytochrome c from mitochondria
GO:0006626	protein targeting to mitochondrion
GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007420	brain development
GO:0008637	apoptotic mitochondrial changes
GO:0032355	response to estradiol
GO:0032464	positive regulation of protein homooligomerization
GO:0034349	glial cell apoptotic process
GO:0042127	regulation of cell proliferation
GO:0043065	positive regulation of apoptotic process
GO:0045087	innate immune response (InnateDB)
GO:0090150	establishment of protein localization to membrane
GO:0090200	positive regulation of release of cytochrome c from mitochondria
GO:0097191	extrinsic apoptotic signaling pathway
GO:1902108	regulation of mitochondrial membrane permeability involved in apoptotic process
GO:2000045	regulation of G1/S transition of mitotic cell cycle
GO:2001238	positive regulation of extrinsic apoptotic signaling pathway

Cellular Component

GO:0005737	cytoplasm
GO:0005739	mitochondrion
GO:0005829	cytosol
GO:0016020	membrane
GO:0032592	integral component of mitochondrial membrane

Protein Structure and Domains

PDB ID

MGI:108093

InterPro

IPR010479 BH3 interacting

PFAM

PF06393

PRINTS

PIRSF

PIRSF038018

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

D3Z463

UniProt Splice Variant

Entrez Gene

12122

UniGene

Mm.235081

RefSeq

MGI ID

MGI Symbol

Bid

OMIM

CCDS

HPRD

IMGT

EMBL

AC083894

GenPept