InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Gart

Summary

InnateDB Protein

IDBP-534747.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gart

Protein Name

phosphoribosylglycinamide formyltransferase

Synonyms

Gaps; Prgs;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000119272

InnateDB Gene

IDBG-176236 (Gart)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	11 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004637	phosphoribosylamine-glycine ligase activity
GO:0005524	ATP binding
GO:0046872	metal ion binding

Biological Process

GO:0009113

purine nucleobase biosynthetic process

Cellular Component

Protein Structure and Domains

PDB ID

MGI:95654

InterPro

IPR000115 Phosphoribosylglycinamide synthetase
IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type
IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain
IPR011761 ATP-grasp fold
IPR016185 Pre-ATP-grasp domain
IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
IPR020562 Phosphoribosylglycinamide synthetase, N-terminal

PFAM

PF02222
PF02786
PF01071
PF02844

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-