InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Vamp1

Summary

InnateDB Protein

IDBP-189642.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Vamp1

Protein Name

vesicle-associated membrane protein 1

Synonyms

lew; Syb-1; Syb1; VAMP-1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000098503

InnateDB Gene

IDBG-189636 (Vamp1)

Protein Structure

UniProt Annotation

Function

Involved in the targeting and/or fusion of transport vesicles to their target membrane.

Subcellular Localization

Isoform 1: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}. Cell junction, synapse, synaptosome {ECO:0000250}.Isoform 2: Cytoplasmic vesicle membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}. Cell junction, synapse, synaptosome {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000149	SNARE binding
GO:0005484	SNAP receptor activity

Biological Process

GO:0006906	vesicle fusion
GO:0007269	neurotransmitter secretion
GO:0016192	vesicle-mediated transport
GO:0017157	regulation of exocytosis
GO:0035493	SNARE complex assembly

Cellular Component

GO:0005739	mitochondrion
GO:0008021	synaptic vesicle
GO:0009986	cell surface
GO:0016021	integral component of membrane
GO:0030054	cell junction
GO:0030672	synaptic vesicle membrane
GO:0031201	SNARE complex
GO:0043005	neuron projection