InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Brwd1

Summary

InnateDB Protein

IDBP-179353.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Brwd1

Protein Name

bromodomain and WD repeat domain containing 1

Synonyms

5330419I02Rik; D530019K20Rik; G1-403-16; repro5; Wdr9;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000097101

InnateDB Gene

IDBG-179349 (Brwd1)

Protein Structure

UniProt Annotation

Function

May be a transcriptional activator. May be involved in chromatin remodeling. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape. {ECO:0000269PubMed:12889071}.

Subcellular Localization

Cytoplasm {ECO:0000269PubMed:12889071}. Nucleus {ECO:0000269PubMed:12889071}.

Disease Associations

Tissue Specificity

Ubiquitously expressed. {ECO:0000269PubMed:12359327}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	12 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0030528	transcription regulator activity

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0007010	cytoskeleton organization
GO:0008360	regulation of cell shape