InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pfkl

Summary

InnateDB Protein

IDBP-168035.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pfkl

Protein Name

phosphofructokinase, liver, B-type

Synonyms

AA407869; ATP-PFK; PFK-L;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000020522

InnateDB Gene

IDBG-168033 (Pfkl)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 28 interaction(s) predicted by orthology.

Experimentally validated
Total	9 [view]
Protein-Protein	7 [view]
Protein-DNA	1 [view]
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	28 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003872	6-phosphofructokinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0019900	kinase binding
GO:0042802	identical protein binding
GO:0046872	metal ion binding
GO:0048029	monosaccharide binding
GO:0070061	fructose binding
GO:0070095	fructose-6-phosphate binding

Biological Process

GO:0005975	carbohydrate metabolic process
GO:0006002	fructose 6-phosphate metabolic process
GO:0006096	glycolytic process
GO:0009749	response to glucose
GO:0030388	fructose 1,6-bisphosphate metabolic process
GO:0046676	negative regulation of insulin secretion
GO:0046835	carbohydrate phosphorylation
GO:0051259	protein oligomerization
GO:0051289	protein homotetramerization