InnateDB Protein
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IDBP-162144.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Cebpe
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Protein Name
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CCAAT/enhancer binding protein (C/EBP), epsilon
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Synonyms
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C/EBPe; CRP1; Gm294;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000068927
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InnateDB Gene
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IDBG-162142 (Cebpe)
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Protein Structure
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Function |
C/EBP are DNA-binding proteins that recognize two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. {ECO:0000250}.
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Subcellular Localization |
Nucleus {ECO:0000255PROSITE- ProRule:PRU00978}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 46 interaction(s) predicted by orthology.
Experimentally validated |
Total |
4
[view]
|
Protein-Protein |
0
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Protein-DNA |
4
[view]
|
Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
46 [view]
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Molecular Function |
Accession |
GO Term |
GO:0000978
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RNA polymerase II core promoter proximal region sequence-specific DNA binding
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GO:0001077
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RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
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GO:0003677
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DNA binding
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GO:0003700
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sequence-specific DNA binding transcription factor activity
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GO:0042803
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protein homodimerization activity
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GO:0043565
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sequence-specific DNA binding
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GO:0046982
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protein heterodimerization activity
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:103572
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InterPro |
IPR004827
Basic-leucine zipper domain
IPR016468
CCAAT/enhancer-binding
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PFAM |
PF00170
PF07716
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PRINTS |
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PIRSF |
PIRSF005879
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SMART |
SM00338
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TIGRFAMs |
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Modification |
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SwissProt |
Q6PZD9
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PhosphoSite |
PhosphoSite-Q6PZD9
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TrEMBL |
Q3UPF8
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UniProt Splice Variant |
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Entrez Gene |
110794
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UniGene |
Mm.236223
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RefSeq |
NP_997014
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MGI ID |
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MGI Symbol |
Cebpe
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OMIM |
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CCDS |
CCDS27100
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HPRD |
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IMGT |
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EMBL |
AK143561
AY570294
BC108953
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GenPept |
AAI08954
AAS78198
BAE25437
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