Mus musculus Gene: Cebpe | |||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Summary | |||||||||||||||||||||||
InnateDB Gene | IDBG-162142.6 | ||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
Gene Symbol | Cebpe | ||||||||||||||||||||||
Gene Name | CCAAT/enhancer binding protein (C/EBP), epsilon | ||||||||||||||||||||||
Synonyms | C/EBPe; CRP1; Gm294 | ||||||||||||||||||||||
Species | Mus musculus | ||||||||||||||||||||||
Ensembl Gene | ENSMUSG00000052435 | ||||||||||||||||||||||
Encoded Proteins |
CCAAT/enhancer binding protein (C/EBP), epsilon
|
||||||||||||||||||||||
Protein Structure | |||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
InnateDB Annotation | |||||||||||||||||||||||
Summary |
Cebpe is a member of the CCAAT enhancer binding protein family and is a transcriptional factor regulating genes in innate immunity and inflammation. The activities of CEBP are regulated via methylation of arginine and lysine side chains.
|
||||||||||||||||||||||
InnateDB Annotation from Orthologs | |||||||||||||||||||||||
Summary |
[Homo sapiens] CEBPE is a member of the CCAAT enhancer binding protein family and is a transcriptional factor regulating genes in innate immunity and inflammation. The activities of CEBP are regulated via methylation of arginine and lysine side chains.
|
||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000092067:
The protein encoded by this gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-delta. The encoded protein may be essential for terminal differentiation and functional maturation of committed granulocyte progenitor cells. Mutations in this gene have been associated with Specific Granule Deficiency, a rare congenital disorder. Multiple variants of this gene have been described, but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008] |
||||||||||||||||||||||
Gene Information | |||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||
Genomic Location | Chromosome 14:54710363-54712174 | ||||||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||||||
Band | C2 | ||||||||||||||||||||||
Transcripts |
|
||||||||||||||||||||||
Interactions | |||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 46 interaction(s) predicted by orthology.
|
||||||||||||||||||||||
Gene Ontology | |||||||||||||||||||||||
Molecular Function |
|
||||||||||||||||||||||
Biological Process |
|
||||||||||||||||||||||
Cellular Component |
|
||||||||||||||||||||||
Orthologs | |||||||||||||||||||||||
Species
Homo sapiens
Bos taurus
|
Gene ID
Gene Order
Not yet available
|
||||||||||||||||||||||
Cross-References | |||||||||||||||||||||||
SwissProt | Q6PZD9 | ||||||||||||||||||||||
TrEMBL | Q3UPF8 | ||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||
Entrez Gene | 110794 | ||||||||||||||||||||||
UniGene | Mm.236223 | ||||||||||||||||||||||
RefSeq | NM_207131 | ||||||||||||||||||||||
OMIM | |||||||||||||||||||||||
CCDS | CCDS27100 | ||||||||||||||||||||||
HPRD | |||||||||||||||||||||||
IMGT | |||||||||||||||||||||||
MGI ID | MGI:103572 | ||||||||||||||||||||||
MGI Symbol | Cebpe | ||||||||||||||||||||||
EMBL | AK143561 AY570294 BC108953 | ||||||||||||||||||||||
GenPept | AAI08954 AAS78198 BAE25437 | ||||||||||||||||||||||
RNA Seq Atlas | 110794 | ||||||||||||||||||||||