Mus musculus Protein: Npy
Summary
InnateDB Protein IDBP-146628.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Npy
Protein Name neuropeptide Y
Synonyms 0710005A05Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000031843
InnateDB Gene IDBG-146626 (Npy)
Protein Structure
UniProt Annotation
Function NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. {ECO:0000250}.
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity One of the most abundant peptides in the nervous system. Also found in some chromaffin cells of the adrenal medulla.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001664 G-protein coupled receptor binding
GO:0005179 hormone activity
Biological Process
GO:0007218 neuropeptide signaling pathway
GO:0008217 regulation of blood pressure
GO:0008343 adult feeding behavior
GO:0021954 central nervous system neuron development
GO:0021987 cerebral cortex development
GO:0031175 neuron projection development
GO:0032100 positive regulation of appetite
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
Protein Structure and Domains
PDB ID MGI:97374
InterPro IPR001955 Pancreatic hormone-like
PFAM PF00159
PRINTS PR00278
PIRSF
SMART SM00309
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P57774
PhosphoSite PhosphoSite-P57774
TrEMBL
UniProt Splice Variant
Entrez Gene 109648
UniGene Mm.154796
RefSeq NP_075945
MGI ID
MGI Symbol Npy
OMIM
CCDS CCDS39488
HPRD
IMGT
EMBL AF273768 AF286198 AF286199 AK002982 BC043012
GenPept AAG00945 AAG01330 AAG01331 AAH43012 BAB22495