Version 5.4
Homo sapiens Gene: SERPINB3
Summary
InnateDB Gene IDBG-4488.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SERPINB3
Gene Name serpin peptidase inhibitor, clade B (ovalbumin), member 3
Synonyms HsT1196; SCC; SCCA-1; SCCA-PD; SCCA1; T4-A
Species Homo sapiens
Ensembl Gene ENSG00000057149
Encoded Proteins
IDBP-4490
serpin peptidase inhibitor, clade B (ovalbumin), member 3
IDBP-4492
serpin peptidase inhibitor, clade B (ovalbumin), member 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 18:63637719-63661963
Strand Reverse strand
Band q21.33
Transcripts
ENST00000283752 ENSP00000283752
ENST00000332821 ENSP00000329498
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
Experimentally validated
Total 17 [view]
Protein-Protein 17 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0001618 virus receptor activity
GO:0004867 serine-type endopeptidase inhibitor activity
Biological Process
GO:0009615 response to virus
GO:0010466 negative regulation of peptidase activity
GO:0010951 negative regulation of endopeptidase activity
GO:0030162 regulation of proteolysis
GO:0043086 negative regulation of catalytic activity
GO:0045861 negative regulation of proteolysis
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Orthologs
No orthologs found for this gene
Pathways
NETPATH
NetPath_4
EGFR1 pathway
REACTOME
KEGG
hsa05146
Amoebiasis pathway
INOH
PID NCI
Cross-References
SwissProt P29508
TrEMBL Q5K684 Q9BYH9
UniProt Splice Variant
Entrez Gene 6317
UniGene Hs.227948
RefSeq NM_006919
HUGO HGNC:10569
OMIM 600517
CCDS CCDS11987
HPRD
IMGT
EMBL AB034984 AB046399 AC069356 AF428135 AF428136 AF428137 AF428138 AF428139 AJ515706 AK222746 AK222753 AK314805 AY190327 AY245778 AY245781 BC005224 BT006748 CH471096 EU852041 S66896 U19556 U19559 U19560 U19562 U19565 U19567 U19568
GenPept AAA86316 AAA86317 AAA97552 AAB20405 AAH05224 AAO11731 AAO92269 AAO92272 AAP35394 AAQ04218 AAQ04219 AAQ04220 AAQ04221 AAQ04222 ACF21012 BAB21524 BAB40772 BAD96466 BAD96473 BAG37332 CAD56658 EAW63156 EAW63157
RNA Seq Atlas 6317

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca