Version 5.4
Homo sapiens Gene: SULT1B1
Summary
InnateDB Gene IDBG-21922.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SULT1B1
Gene Name sulfotransferase family, cytosolic, 1B, member 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000173597
Encoded Proteins
IDBP-21924
sulfotransferase family, cytosolic, 1B, member 1
IDBP-474873
sulfotransferase family, cytosolic, 1B, member 1
IDBP-478714
sulfotransferase family, cytosolic, 1B, member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. However, the total genomic length of this gene is greater than that of other SULT1 genes. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:69721162-69787961
Strand Reverse strand
Band q13.3
Transcripts
ENST00000310613 ENSP00000308770
ENST00000510821 ENSP00000425464
ENST00000512870 ENSP00000427536
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004062 aryl sulfotransferase activity
GO:0008146 sulfotransferase activity
Biological Process
GO:0006576 cellular biogenic amine metabolic process
GO:0006805 xenobiotic metabolic process
GO:0008152 metabolic process
GO:0008202 steroid metabolic process
GO:0009812 flavonoid metabolic process
GO:0018958 phenol-containing compound metabolic process
GO:0030855 epithelial cell differentiation
GO:0042403 thyroid hormone metabolic process
GO:0044281 small molecule metabolic process
GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process
GO:0051923 sulfation
Cellular Component
GO:0005829 cytosol
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000029269
View Gene Order
ENSBTAG00000001249
Not yet available
Pathways
NETPATH
REACTOME
REACT_6913
Cytosolic sulfonation of small molecules pathway
REACT_6959
Phase II conjugation pathway
REACT_111217
Metabolism pathway
REACT_13433
Biological oxidations pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt O43704
TrEMBL D6RD70 D6RIA8
UniProt Splice Variant
Entrez Gene 27284
UniGene Hs.129742
RefSeq NM_014465 XM_005265677 XM_005265678
HUGO HGNC:17845
OMIM 608436
CCDS CCDS3530
HPRD
IMGT
EMBL AC108941 AC125239 AF184894 BC010895 D89479 U95726
GenPept AAB65154 AAF05917 AAH10895 BAA24547
RNA Seq Atlas 27284

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca