Version 5.4
Bos taurus Gene: SIK1
Summary
InnateDB Gene IDBG-639805.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SIK1
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000011437
Encoded Proteins
IDBP-692001
salt-inducible kinase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000142178:
Gene Information
Type Protein coding
Genomic Location Chromosome 1:146207250-146216697
Strand Reverse strand
Band
Transcripts
ENSBTAT00000015200 ENSBTAP00000015200
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0000287 magnesium ion binding
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008140 cAMP response element binding protein binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0019901 protein kinase binding
GO:0042826 histone deacetylase binding
Biological Process
GO:0006468 protein phosphorylation
GO:0007346 regulation of mitotic cell cycle
GO:0010830 regulation of myotube differentiation
GO:0010868 negative regulation of triglyceride biosynthetic process
GO:0032792 negative regulation of CREB transcription factor activity
GO:0035556 intracellular signal transduction
GO:0043276 anoikis
GO:0045595 regulation of cell differentiation
GO:0045721 negative regulation of gluconeogenesis
GO:0055007 cardiac muscle cell differentiation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000142178
View Gene Order
ENSMUSG00000024042
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_7
TGF_beta_Receptor pathway
REACTOME
KEGG
INOH
PID NCI
lkb1_pathway
LKB1 signaling events
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca