Version 5.4
Bos taurus Gene: APOBEC1
Summary
InnateDB Gene IDBG-639768.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol APOBEC1
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000014683
Encoded Proteins
IDBP-691957
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000111701:
This gene encodes a member of the cytidine deaminase enzyme family. The encoded protein forms a multiple-protein editing holoenzyme with APOBEC1 complementation factor (ACF) and APOBEC1 stimulating protein (ASP). This holoenzyme is involved in the editing of C-to-U nucleotide bases in apolipoprotein B and neurofibromatosis-1 mRNAs. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:101725366-101730873
Strand Reverse strand
Band
Transcripts
ENSBTAT00000019544 ENSBTAP00000019544
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
GO:0017091 AU-rich element binding
Biological Process
GO:0010332 response to gamma radiation
GO:0016554 cytidine to uridine editing
GO:0016556 mRNA modification
GO:0042127 regulation of cell proliferation
GO:0042157 lipoprotein metabolic process
GO:0042158 lipoprotein biosynthetic process
GO:0042953 lipoprotein transport
GO:0048255 mRNA stabilization
GO:0080111 DNA demethylation
GO:0090310 negative regulation of methylation-dependent chromatin silencing
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000111701
View Gene Order
ENSMUSG00000040613
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_1390
Formation of the Editosome pathway
REACT_167
mRNA Editing: C to U Conversion pathway
REACT_1757
mRNA Editing pathway
REACT_71
Gene Expression pathway
REACT_256546
Formation of the Editosome pathway
REACT_254064
mRNA Editing: C to U Conversion pathway
REACT_233572
Gene Expression pathway
REACT_261262
mRNA Editing pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.63664
RefSeq XM_002687817 XM_594173
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca