Version 5.4
Bos taurus Gene: TMPRSS15
Summary
InnateDB Gene IDBG-630405.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TMPRSS15
Gene Name Enteropeptidase Enteropeptidase non-catalytic heavy chain Enteropeptidase catalytic light chain
Synonyms PRSS7
Species Bos taurus
Ensembl Gene ENSBTAG00000000597
Encoded Proteins
IDBP-681898
EnteropeptidaseEnteropeptidase non-catalytic heavy chainEnteropeptidase catalytic light chain
IDBP-681899
EnteropeptidaseEnteropeptidase non-catalytic heavy chainEnteropeptidase catalytic light chain
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000154646:
This gene encodes an enzyme that converts the pancreatic proenzyme trypsinogen to trypsin, which activates other proenzymes including chymotrypsinogen and procarboxypeptidases. The precursor protein is cleaved into two chains that form a heterodimer linked by a disulfide bond. This protein is a member of the trypsin family of peptidases. Mutations in this gene cause enterokinase deficiency, a malabsorption disorder characterized by diarrhea and failure to thrive. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:18058709-18207251
Strand Forward strand
Band
Transcripts
ENSBTAT00000000788 ENSBTAP00000000788
ENSBTAT00000064206 ENSBTAP00000054149
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
GO:0005044 scavenger receptor activity
GO:0005515 protein binding
GO:0008233 peptidase activity
GO:0008236 serine-type peptidase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006508 proteolysis
GO:0006898 receptor-mediated endocytosis
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000154646
View Gene Order
ENSMUSG00000022857
View Gene Order
Cross-References
SwissProt P98072
TrEMBL
UniProt Splice Variant
Entrez Gene 282009
UniGene Bt.66152
RefSeq NM_174439
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL L19663 U09859
GenPept AAA16035 AAB40026
RNA Seq Atlas 282009

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca