Version 5.4
Mus musculus Gene: Tmprss15
Summary
InnateDB Gene IDBG-172157.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tmprss15
Gene Name transmembrane protease, serine 15
Synonyms Entk; Prss7
Species Mus musculus
Ensembl Gene ENSMUSG00000022857
Encoded Proteins
IDBP-172159
transmembrane protease, serine 15
IDBP-172161
transmembrane protease, serine 15
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes an enzyme that proteolytically activates the pancreatic proenzyme trypsinogen, converting it into trypsin. The encoded protein is cleaved into two chains that form a heterodimer linked by a disulfide bond. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:78953008-79091097
Strand Reverse strand
Band C3.2
Transcripts
ENSMUST00000023566 ENSMUSP00000023566
ENSMUST00000060402 ENSMUSP00000052034
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
GO:0005044 scavenger receptor activity
GO:0005515 protein binding
Biological Process
GO:0006508 proteolysis
GO:0006898 receptor-mediated endocytosis
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000154646
View Gene Order
ENSBTAG00000000597
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.5184
RefSeq NM_008941 NM_178855
OMIM
CCDS CCDS28280 CCDS37380
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca