Version 5.4
Mus musculus Gene: Evl
Summary
InnateDB Gene IDBG-170758.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Evl
Gene Name Ena-vasodilator stimulated phosphoprotein
Synonyms AI528774
Species Mus musculus
Ensembl Gene ENSMUSG00000021262
Encoded Proteins
IDBP-170760
Ena-vasodilator stimulated phosphoprotein
IDBP-170762
Ena-vasodilator stimulated phosphoprotein
IDBP-261510
Ena-vasodilator stimulated phosphoprotein
IDBP-622903
Ena-vasodilator stimulated phosphoprotein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000196405:
Gene Information
Type Protein coding
Genomic Location Chromosome 12:108554720-108688513
Strand Forward strand
Band F1
Transcripts
ENSMUST00000077735 ENSMUSP00000076916
ENSMUST00000021689 ENSMUSP00000021689
ENSMUST00000109854 ENSMUSP00000105480
ENSMUST00000172409 ENSMUSP00000133072
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 8 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 21 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
GO:0005522 profilin binding
GO:0017124 SH3 domain binding
Biological Process
GO:0007411 axon guidance
GO:0008154 actin polymerization or depolymerization
GO:0010633 negative regulation of epithelial cell migration
GO:0030048 actin filament-based movement
GO:0030168 platelet activation
GO:0030838 positive regulation of actin filament polymerization
GO:0045010 actin nucleation
GO:0051016 barbed-end actin filament capping
GO:0051289 protein homotetramerization
GO:0051496 positive regulation of stress fiber assembly
GO:1900028 negative regulation of ruffle assembly
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005925 focal adhesion
GO:0016020 membrane
GO:0030027 lamellipodium
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000196405
View Gene Order
ENSBTAG00000009293
Not yet available
Pathways
NETPATH
REACTOME
REACT_230745
Immune System pathway
REACT_221567
Signaling by Robo receptor pathway
REACT_261444
Axon guidance pathway
REACT_229531
Adaptive Immune System pathway
REACT_188576
Developmental Biology pathway
REACT_225768
Generation of second messenger molecules pathway
REACT_222648
TCR signaling pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_11
TCR pathway
REACTOME
REACT_12623
Generation of second messenger molecules pathway
REACT_19351
Signaling by Robo receptor pathway
REACT_111045
Developmental Biology pathway
REACT_12526
TCR signaling pathway
REACT_18266
Axon guidance pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt P70429
TrEMBL E9PVP4 F8WJB9
UniProt Splice Variant
Entrez Gene 14026
UniGene Mm.238841
RefSeq NM_001163394 NM_001163395 NM_001163396 NM_007965 XM_006515470 XM_006515471
OMIM
CCDS CCDS26161 CCDS49167 CCDS49168 CCDS49169
HPRD
IMGT
MGI ID MGI:1194884
MGI Symbol Evl
EMBL AC137155 AC139568 AF279662 U72519
GenPept AAC52862 AAG23653
RNA Seq Atlas 14026

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca