InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Igfbp1

Summary

InnateDB Gene

IDBG-148835.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Igfbp1

Gene Name

insulin-like growth factor binding protein 1

Synonyms

Species

Mus musculus

Ensembl Gene

ENSMUSG00000020429

Encoded Proteins

IDBP-148837

insulin-like growth factor binding protein 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000146678:
This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 11:7197782-7202546

Strand

Forward strand

Band

Transcripts

ENSMUST00000020704

ENSMUSP00000020704

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	2 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005520	insulin-like growth factor binding

Biological Process

GO:0001558	regulation of cell growth
GO:0008286	insulin receptor signaling pathway
GO:0030307	positive regulation of cell growth
GO:0042246	tissue regeneration