InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Dbnl

Summary

InnateDB Gene

IDBG-145110.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Dbnl

Gene Name

drebrin-like

Synonyms

Abp1; mAbp1; SH3P7

Species

Mus musculus

Ensembl Gene

ENSMUSG00000020476

Encoded Proteins

IDBP-145112

drebrin-like

IDBP-145114

drebrin-like

IDBP-261516

drebrin-like

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000136279:

Gene Information

Type

Protein coding

Genomic Location

Chromosome 11:5788488-5800962

Strand

Forward strand

Band

Transcripts

ENSMUST00000020769	ENSMUSP00000020769
ENSMUST00000102928	ENSMUSP00000099992
ENSMUST00000109845	ENSMUSP00000105471

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.

Experimentally validated
Total	14 [view]
Protein-Protein	14 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	21 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003779	actin binding
GO:0005515	protein binding
GO:0008022	protein C-terminus binding
GO:0019904	protein domain specific binding
GO:0051015	actin filament binding

Biological Process

GO:0002376	immune system process
GO:0006897	endocytosis
GO:0007416	synapse assembly
GO:0016601	Rac protein signal transduction
GO:0048812	neuron projection morphogenesis
GO:0071800	podosome assembly

Cellular Component

GO:0000139	Golgi membrane
GO:0001726	ruffle
GO:0002102	podosome
GO:0005622	intracellular
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005886	plasma membrane
GO:0005938	cell cortex
GO:0014069	postsynaptic density
GO:0030027	lamellipodium
GO:0030054	cell junction
GO:0030425	dendrite
GO:0030665	clathrin-coated vesicle membrane
GO:0070062	extracellular vesicular exosome

Orthologs

Species

Homo sapiens

Bos taurus

Gene ID

Gene Order

ENSG00000136279

View Gene Order

ENSBTAG00000017547

Not yet available

Pathways

NETPATH

REACTOME

REACT_258521

Apoptosis pathway

REACT_224460

Apoptotic cleavage of cellular proteins pathway

REACT_210562

Caspase-mediated cleavage of cytoskeletal proteins pathway

REACT_207035

Apoptotic execution phase pathway

KEGG

INOH

PID NCI

Pathway Predictions based on Human Orthology Data

NETPATH

NetPath_11

TCR pathway

NetPath_12

BCR pathway

NetPath_24

TSLP pathway

REACTOME

REACT_13541

Caspase-mediated cleavage of cytoskeletal proteins pathway

REACT_107

Apoptotic cleavage of cellular proteins pathway

REACT_995

Apoptotic execution phase pathway

REACT_578

Apoptosis pathway

REACT_219628

Apoptotic cleavage of cellular proteins pathway

REACT_218975

Caspase-mediated cleavage of cytoskeletal proteins pathway

REACT_227007

Apoptotic execution phase pathway

REACT_219454

Apoptosis pathway

KEGG

INOH

PID NCI

tcr_pathway

TCR signaling in na�ve CD4+ T cells

tcrjnkpathway

JNK signaling in the CD4+ TCR pathway

Cross-References

SwissProt

Q62418

TrEMBL

UniProt Splice Variant

Entrez Gene

13169

UniGene

RefSeq

NM_001146308 NM_001146309 NM_013810

OMIM

CCDS

CCDS24403 CCDS48746 CCDS48747

HPRD

IMGT

MGI ID

MGI:700006

MGI Symbol

Dbnl

EMBL

AK046073 AK053796 AK078082 AK134136 AK134487 AK140752 AK142818 AK146920 AK151096 AK152204 AK153389 AK159984 AK168898 AK172471 AL627069 AY098595 BC046430 U58884

GenPept

AAC52640 AAH46430 AAM28340 BAC32592 BAC35528 BAC37118 BAE22028 BAE22160 BAE24466 BAE25201 BAE27532 BAE30108 BAE31033 BAE31953 BAE35535 BAE40714 BAE43024 CAI25434 CAI25435 CAI25436

RNA Seq Atlas

13169