Version 5.4
Mus musculus Gene: Eif4enif1
Summary
InnateDB Gene IDBG-138652.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Eif4enif1
Gene Name eukaryotic translation initiation factor 4E nuclear import factor 1
Synonyms 2610509L04Rik; A930019J01Rik; AA410001; AU021239; Clast4; D11Ertd166e
Species Mus musculus
Ensembl Gene ENSMUSG00000020454
Encoded Proteins
IDBP-138654
eukaryotic translation initiation factor 4E nuclear import factor 1
IDBP-261092
eukaryotic translation initiation factor 4E nuclear import factor 1
IDBP-261094
eukaryotic translation initiation factor 4E nuclear import factor 1
IDBP-401356
eukaryotic translation initiation factor 4E nuclear import factor 1
IDBP-541674
eukaryotic translation initiation factor 4E nuclear import factor 1
IDBP-537278
eukaryotic translation initiation factor 4E nuclear import factor 1
IDBP-718611
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000184708:
The protein encoded by this gene is a nucleocytoplasmic shuttle protein for the translation initiation factor eIF4E. This shuttle protein interacts with the importin alpha-beta complex to mediate nuclear import of eIF4E. It is predominantly cytoplasmic; its own nuclear import is regulated by a nuclear localization signal and nuclear export signals. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:3202392-3244588
Strand Forward strand
Band A1
Transcripts
ENSMUST00000020734 ENSMUSP00000020734
ENSMUST00000110049 ENSMUSP00000105676
ENSMUST00000110048 ENSMUSP00000105675
ENSMUST00000120721 ENSMUSP00000112550
ENSMUST00000125224
ENSMUST00000131693
ENSMUST00000125637 ENSMUSP00000118527
ENSMUST00000132425
ENSMUST00000143770
ENSMUST00000135223 ENSMUSP00000122912
ENSMUST00000127950
ENSMUST00000147534
ENSMUST00000179770 ENSMUSP00000136768
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Experimentally validated
Total 13 [view]
Protein-Protein 10 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0008150 biological_process
GO:0015031 protein transport
Cellular Component
GO:0005634 nucleus
GO:0005829 cytosol
GO:0016020 membrane
GO:0016605 PML body
GO:0016607 nuclear speck
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000184708
View Gene Order
ENSBTAG00000008991
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.255649 Mm.328437
RefSeq NM_001166547 NM_001166548 NM_001166549 NM_023743 XM_006514841 XM_006514842 XM_006514843 XM_006514844
OMIM
CCDS CCDS24354 CCDS48739
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca