Homo sapiens Gene: TAS2R1
Summary
InnateDB Gene IDBG-12243.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TAS2R1
Gene Name taste receptor, type 2, member 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000169777
Encoded Proteins
taste receptor, type 2, member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily and that are specifically expressed by taste receptor cells of the tongue and palate epithelia. This intronless taste receptor gene encodes a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is mapped to chromosome 5p15, the location of a genetic locus (PROP) that controls the detection of the bitter compound 6-n-propyl-2-thiouracil. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:9628997-9712378
Strand Reverse strand
Band p15.31
Transcripts
ENST00000382492 ENSP00000371932
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0008527 taste receptor activity
GO:0033038 bitter taste receptor activity
Biological Process
GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007635 chemosensory behavior
GO:0050909 sensory perception of taste
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
G alpha (i) signalling events pathway
Class C/3 (Metabotropic glutamate/pheromone receptors) pathway
Signaling by GPCR pathway
Signal Transduction pathway
GPCR downstream signaling pathway
GPCR ligand binding pathway
KEGG
Taste transduction pathway
INOH
PID NCI
Cross-References
SwissProt Q9NYW7
TrEMBL Q50L07 U3KPZ8 U3KQT0
UniProt Splice Variant
Entrez Gene 50834
UniGene Hs.567492
RefSeq NM_019599
HUGO HGNC:14909
OMIM 604796
CCDS CCDS3876
HPRD
IMGT
EMBL AB198983 AB198985 AC026787 AC034214 AF227129 AY724812 BC101729 BC101731
GenPept AAF43902 AAI01730 AAI01732 AAU21051 BAD97889 BAD97891
RNA Seq Atlas 50834