InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: BRSK2

Summary

InnateDB Protein

IDBP-698308.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BRSK2

Protein Name

BR serine/threonine kinase 2

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000023759

InnateDB Gene

IDBG-645584 (BRSK2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000287	magnesium ion binding
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0019901	protein kinase binding
GO:0050321	tau-protein kinase activity

Biological Process

GO:0000086	G2/M transition of mitotic cell cycle
GO:0006468	protein phosphorylation
GO:0007409	axonogenesis
GO:0018105	peptidyl-serine phosphorylation
GO:0030010	establishment of cell polarity
GO:0030182	neuron differentiation
GO:0031532	actin cytoskeleton reorganization
GO:0048812	neuron projection morphogenesis
GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

Cellular Component

GO:0005737	cytoplasm
GO:0005813	centrosome

Protein Structure and Domains

PDB ID

InterPro

IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002290 Serine/threonine/dual specificity protein kinase, catalytic domain
IPR011009 Protein kinase-like domain
IPR020635 Tyrosine-protein kinase, catalytic domain

PFAM

PF00069
PF07714

PRINTS

PR00109

PIRSF

SMART

SM00220
SM00219

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt