Version 5.4
Bos taurus Protein: ADAM9
Summary
InnateDB Protein IDBP-680809.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ADAM9
Protein Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000023197
InnateDB Gene IDBG-629406 (ADAM9)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004222 metalloendopeptidase activity
GO:0005080 protein kinase C binding
GO:0005515 protein binding
GO:0005518 collagen binding
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
GO:0017124 SH3 domain binding
GO:0043236 laminin binding
Biological Process
GO:0000186 activation of MAPKK activity
GO:0006508 proteolysis
GO:0006509 membrane protein ectodomain proteolysis
GO:0007155 cell adhesion
GO:0007160 cell-matrix adhesion
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0007229 integrin-mediated signaling pathway
GO:0010042 response to manganese ion
GO:0030216 keratinocyte differentiation
GO:0033627 cell adhesion mediated by integrin
GO:0033630 positive regulation of cell adhesion mediated by integrin
GO:0033631 cell-cell adhesion mediated by integrin
GO:0034241 positive regulation of macrophage fusion
GO:0034612 response to tumor necrosis factor
GO:0042117 monocyte activation
GO:0042542 response to hydrogen peroxide
GO:0050714 positive regulation of protein secretion
GO:0051044 positive regulation of membrane protein ectodomain proteolysis
GO:0051088 PMA-inducible membrane protein ectodomain proteolysis
GO:0051384 response to glucocorticoid
GO:0051549 positive regulation of keratinocyte migration
GO:0051592 response to calcium ion
GO:0071222 cellular response to lipopolysaccharide
Cellular Component
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0009986 cell surface
GO:0031233 intrinsic to external side of plasma membrane
Protein Structure and Domains
PDB ID
InterPro IPR000742 Epidermal growth factor-like domain
IPR001590 Peptidase M12B, ADAM/reprolysin
IPR001762 Blood coagulation inhibitor, Disintegrin
IPR002870 Peptidase M12B, propeptide
IPR006586 ADAM, cysteine-rich
PFAM PF00008
PF01421
PF00200
PF01562
PF08516
PRINTS PR00289
PIRSF
SMART SM00181
SM00050
SM00608
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL O77635
UniProt Splice Variant
Entrez Gene 281600
UniGene Bt.734
RefSeq NP_001179747
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AF069647 DAAA02060867
GenPept AAC23531

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca