Version 5.4
Mus musculus Protein: Rfc1
Summary
InnateDB Protein IDBP-628170.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rfc1
Protein Name replication factor C (activator 1) 1
Synonyms 140kDa; Alp145; Recc1; RFC140;
Species Mus musculus
Ensembl Protein ENSMUSP00000133738
InnateDB Gene IDBG-166380 (Rfc1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 42 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 42 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003677 DNA binding
GO:0003689 DNA clamp loader activity
GO:0005524 ATP binding
GO:0017111 nucleoside-triphosphatase activity
Biological Process
GO:0006200 ATP catabolic process
GO:0006260 DNA replication
Cellular Component
GO:0005634 nucleus
GO:0005663 DNA replication factor C complex
Protein Structure and Domains
PDB ID MGI:97891
InterPro IPR001357 BRCT domain
IPR003593 AAA+ ATPase domain
IPR003959 ATPase, AAA-type, core
IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal
IPR012178 DNA replication factor C, large subunit
IPR013725 DNA replication factor RFC1, C-terminal
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00533
PF12738
PF00004
PF07724
PF13304
PF08519
PRINTS
PIRSF PIRSF036578
SMART SM00292
SM00382
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q3V247
UniProt Splice Variant
Entrez Gene 19687
UniGene Mm.148877
RefSeq
MGI ID
MGI Symbol Rfc1
OMIM
CCDS
HPRD
IMGT
EMBL AC138654 AK132028 AK143077
GenPept BAE20952 BAE25264

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca