InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SKP2

Summary

InnateDB Protein

IDBP-598612.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SKP2

Protein Name

S-phase kinase-associated protein 2 (p45)

Synonyms

FBL1; FBXL1; FLB1; p45;

Species

Homo sapiens

Ensembl Protein

ENSP00000443492

InnateDB Gene

IDBG-16420 (SKP2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 176 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Experimentally validated
Total	176 [view]
Protein-Protein	168 [view]
Protein-DNA	7 [view]
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0042802	identical protein binding

Biological Process

GO:0000082	G1/S transition of mitotic cell cycle
GO:0000278	mitotic cell cycle
GO:0008283	cell proliferation
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process

Cellular Component

GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0016235	aggresome
GO:0019005	SCF ubiquitin ligase complex