InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: TP53BP1

Summary

InnateDB Protein

IDBP-369449.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TP53BP1

Protein Name

tumor protein p53 binding protein 1

Synonyms

53BP1; p202;

Species

Homo sapiens

Ensembl Protein

ENSP00000393497

InnateDB Gene

IDBG-8462 (TP53BP1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 162 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.

Experimentally validated
Total	162 [view]
Protein-Protein	160 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	1 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	11 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001102	RNA polymerase II activating transcription factor binding
GO:0001104	RNA polymerase II transcription cofactor activity
GO:0002039	p53 binding
GO:0005515	protein binding
GO:0035064	methylated histone binding

Biological Process

GO:0000724	double-strand break repair via homologous recombination
GO:0006281	DNA repair
GO:0006302	double-strand break repair
GO:0006366	transcription from RNA polymerase II promoter
GO:0006974	cellular response to DNA damage stimulus
GO:0045893	positive regulation of transcription, DNA-templated
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0051091	positive regulation of sequence-specific DNA binding transcription factor activity