Version 5.4
Homo sapiens Protein: TATDN2
Summary
InnateDB Protein IDBP-362847.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TATDN2
Protein Name TatD DNase domain containing 2
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000408736
InnateDB Gene IDBG-17948 (TATDN2)
Protein Structure
UniProt Annotation
Function Putative deoxyribonuclease. {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004536 deoxyribonuclease activity
GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters
GO:0046872 metal ion binding
Biological Process
GO:0000737 DNA catabolic process, endonucleolytic
GO:0006308 DNA catabolic process
GO:0006987 activation of signaling protein activity involved in unfolded protein response
GO:0030968 endoplasmic reticulum unfolded protein response
GO:0044267 cellular protein metabolic process
Cellular Component
GO:0005654 nucleoplasm
GO:0043229 intracellular organelle
Protein Structure and Domains
PDB ID
InterPro IPR001130 TatD family
PFAM PF01026
PRINTS
PIRSF PIRSF005902
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q93075
PhosphoSite PhosphoSite-Q93075
TrEMBL H7BZJ2
UniProt Splice Variant
Entrez Gene 9797
UniGene Hs.737384
RefSeq
HUGO HGNC:28988
OMIM
CCDS CCDS33698
HPRD 18712
IMGT
EMBL AC022384 BC090935 BC101770 BC101776 CH471055 D86972
GenPept AAH90935 AAI01771 AAI01777 BAA13208 EAW64070 EAW64071 EAW64072

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca