Version 5.4
Mus musculus Protein: Plin3
Summary
InnateDB Protein IDBP-191945.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Plin3
Protein Name perilipin 3
Synonyms 1300012C15Rik; M6prbp1; Tip47;
Species Mus musculus
Ensembl Protein ENSMUSP00000019726
InnateDB Gene IDBG-191943 (Plin3)
Protein Structure
UniProt Annotation
Function Required for the transport of mannose 6-phosphate receptors (MPR) from endosomes to the trans-Golgi network. {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}. Endosome membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Lipid droplet {ECO:0000250}. Note=Membrane associated on endosomes. Detected in the envelope and the core of lipid bodies and in lipid sails (By similarity). {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 18 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006810 transport
Cellular Component
GO:0005737 cytoplasm
GO:0005811 lipid particle
GO:0010008 endosome membrane
GO:0016020 membrane
GO:0043231 intracellular membrane-bounded organelle
Protein Structure and Domains
PDB ID MGI:1914155
InterPro IPR004279 Perilipin
PFAM PF03036
PRINTS
PIRSF PIRSF036881
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9DBG5
PhosphoSite PhosphoSite-Q9DBG5
TrEMBL Q3V4D2
UniProt Splice Variant
Entrez Gene 66905
UniGene Mm.311696
RefSeq NP_080112
MGI ID 1SZI
MGI Symbol Plin3
OMIM
CCDS CCDS28901
HPRD
IMGT
EMBL AK003971 AK004970 AK012517 AK049537 AK050140 AK132313 AK167214 BC011116
GenPept AAH11116 BAB23708 BAB28291 BAC33798 BAC34089 BAE21098 BAE39340 BAE43154

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca