InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SLC30A9

Summary

InnateDB Protein

IDBP-15704.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SLC30A9

Protein Name

solute carrier family 30 (zinc transporter), member 9

Synonyms

C4orf1; GAC63; HUEL; ZNT9;

Species

Homo sapiens

Ensembl Protein

ENSP00000264451

InnateDB Gene

IDBG-15702 (SLC30A9)

Protein Structure

UniProt Annotation

Function

Plays a role in the p160 coactivator signaling pathway that mediates transcriptional activation by nuclear receptors. Plays a role in transcriptional activation of Wnt-responsive genes. {ECO:0000250}.

Subcellular Localization

Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Nucleus {ECO:0000269PubMed:10409434}.

Disease Associations

Tissue Specificity

Ubiquitously expressed in fetal and adult tissues and cancer cell lines. {ECO:0000269PubMed:10409434}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.

Experimentally validated
Total	5 [view]
Protein-Protein	2 [view]
Protein-DNA	2 [view]
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003682	chromatin binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0008324	cation transmembrane transporter activity
GO:0016922	ligand-dependent nuclear receptor binding
GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity

Biological Process

GO:0006289	nucleotide-excision repair
GO:0006351	transcription, DNA-templated
GO:0006812	cation transport
GO:0006829	zinc ion transport
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0055085	transmembrane transport