Homo sapiens Gene: WDHD1
Summary
InnateDB Gene IDBG-7169.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol WDHD1
Gene Name WD repeat and HMG-box DNA binding protein 1
Synonyms AND-1; CHTF4; CTF4;
Species Homo sapiens
Ensembl Gene ENSG00000198554
Encoded Proteins
WD repeat and HMG-box DNA binding protein 1
WD repeat and HMG-box DNA binding protein 1
WD repeat and HMG-box DNA binding protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene contains multiple N-terminal WD40 domains and a C-terminal high mobility group (HMG) box. WD40 domains are found in a variety of eukaryotic proteins and may function as adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. HMG boxes are found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:54938950-55027105
Strand Reverse strand
Band q22.3
Transcripts
ENST00000360586 ENSP00000353793
ENST00000420358 ENSP00000399349
ENST00000455555 ENSP00000413435
ENST00000475379
ENST00000567693 ENSP00000456806
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 32 experimentally validated interaction(s) in this database.
Experimentally validated
Total 32 [view]
Protein-Protein 30 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0070063 RNA polymerase binding
Biological Process
GO:0006396 RNA processing
GO:0033044 regulation of chromosome organization
GO:0070829 heterochromatin maintenance
Cellular Component
GO:0000775 chromosome, centromeric region
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.385998 Hs.603079
RefSeq NM_001008396 NM_007086 XM_005267294 XM_006720012
HUGO
OMIM
CCDS CCDS41955 CCDS9721
HPRD 10483
IMGT
EMBL
GenPept
RNA Seq Atlas