Version 5.4
Homo sapiens Gene: TATDN2
Summary
InnateDB Gene IDBG-17948.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TATDN2
Gene Name TatD DNase domain containing 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000157014
Encoded Proteins
IDBP-17950
TatD DNase domain containing 2
IDBP-362847
TatD DNase domain containing 2
IDBP-362850
TatD DNase domain containing 2
IDBP-362851
TatD DNase domain containing 2
IDBP-362852
TatD DNase domain containing 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 3:10248023-10281218
Strand Forward strand
Band p25.3
Transcripts
ENST00000287652 ENSP00000287652
ENST00000448281 ENSP00000408736
ENST00000437082 ENSP00000402783
ENST00000450534 ENSP00000399689
ENST00000426850 ENSP00000389896
ENST00000496355
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004536 deoxyribonuclease activity
GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters
GO:0046872 metal ion binding
Biological Process
GO:0000737 DNA catabolic process, endonucleolytic
GO:0006308 DNA catabolic process
GO:0006987 activation of signaling protein activity involved in unfolded protein response
GO:0030968 endoplasmic reticulum unfolded protein response
GO:0044267 cellular protein metabolic process
Cellular Component
GO:0005654 nucleoplasm
GO:0043229 intracellular organelle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000056952
View Gene Order
ENSBTAG00000019479
Not yet available
Pathways
NETPATH
REACTOME
REACT_18273
XBP1(S) activates chaperone genes pathway
REACT_18368
IRE1alpha activates chaperones pathway
REACT_18356
Unfolded Protein Response (UPR) pathway
REACT_17015
Metabolism of proteins pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.475401 Hs.737384
RefSeq NM_014760
HUGO
OMIM
CCDS CCDS33698
HPRD 18712
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca