Homo sapiens Gene: PHKG1
Summary
InnateDB Gene IDBG-17586.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PHKG1
Gene Name phosphorylase kinase, gamma 1 (muscle)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000164776
Encoded Proteins
phosphorylase kinase, gamma 1 (muscle)
phosphorylase kinase, gamma 1 (muscle)
phosphorylase kinase, gamma 1 (muscle)
phosphorylase kinase, gamma 1 (muscle)
phosphorylase kinase, gamma 1 (muscle)
phosphorylase kinase, gamma 1 (muscle)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is a member of the Ser/Thr protein kinase family and encodes a protein with one protein kinase domain and two calmodulin-binding domains. This protein is the catalytic member of a 16 subunit protein kinase complex which contains equimolar ratios of 4 subunit types. The complex is a crucial glycogenolytic regulatory enzyme. This gene has two pseudogenes at chromosome 7q11.21 and one at chromosome 11p11.12. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:56080283-56092996
Strand Reverse strand
Band p11.2
Transcripts
ENST00000297373 ENSP00000297373
ENST00000395428 ENSP00000378817
ENST00000446428 ENSP00000389721
ENST00000432123 ENSP00000397193
ENST00000452681 ENSP00000445440
ENST00000471665
ENST00000489604
ENST00000467726
ENST00000492124
ENST00000537360 ENSP00000441528
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004689 phosphorylase kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005516 calmodulin binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0016773 phosphotransferase activity, alcohol group as acceptor
GO:0019899 enzyme binding
GO:0050321 tau-protein kinase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0005977 glycogen metabolic process
GO:0005978 glycogen biosynthetic process
GO:0005980 glycogen catabolic process
GO:0006006 glucose metabolic process
GO:0006468 protein phosphorylation
GO:0009103 lipopolysaccharide biosynthetic process
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005829 cytosol
GO:0005964 phosphorylase kinase complex
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Myoclonic epilepsy of Lafora pathway
Metabolism of carbohydrates pathway
Glycogen breakdown (glycogenolysis) pathway
Metabolism pathway
Disease pathway
Glucose metabolism pathway
Glycogen storage diseases pathway
KEGG
Calcium signaling pathway pathway
Insulin signaling pathway pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.730821 Hs.741525
RefSeq NM_001258459 NM_001258460 NM_006213
HUGO
OMIM
CCDS CCDS5525 CCDS59057
HPRD 01404
IMGT
EMBL
GenPept
RNA Seq Atlas